Digital drug hunter active in artificial intelligence and knowledge management for target and drug discovery. Two drugs in clinical trials: R-ketorolac for in ovarian cancer, and LNS8801, a first-in-class orphan drug designated GPER agonist for uveal melanoma. Conceptual developments in disease and chemical biology include lead-likeness, systems chemical biology, temporal disease trajectories, and a knowledge-based classification of human proteins. Co-creator of the open-source platforms DrugCentral and Pharos. Currently CEO of Expert Systems Inc, a San Diego-based drug discovery accelerator, and Professor Emeritus of Medicine, University of New Mexico, Albuquerque NM.
After briefly discussing artificial intelligence and its general impact and introducing Expert Systems, we will explore the use of AI and machine learning in drug discovery and repurposing. An example of using AI as Research Agents will be presented.