Shona Gray-Switzman | ProteoGenix
Shona has a Master Degree in molecular biology & genetics, she has been graduated of the University of Paris, in 2019.
Appearances:
Festival of Biologics Day 1 @ 14:40
Combining innovative technologies to overcome the multiple challenges of neutralizing antibody discovery in Cancer therapy
Though Phage Display has been instrumental in therapeutic antibody development, new challenges have appeared. Neutralizing antibodies can be difficult to obtain from naïve human libraries due to lower affinity & self-tolerance. Combining innovative technologies such as Phage Display libraries supplemented with disease specific patient samples, NGS, AI & humanized mice for single B-cell sorting maximizes the chances of identifying neutralizing antibodies against any target, in particular for autoimmune disorders & cancer.
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