Jintang He | Senior Principal Scientist
Genentech

Jintang He, Senior Principal Scientist, Genentech

Dr. Jintang He is currently a Senior Principal Scientist in the BioAnalytical Sciences department at Genentech. He received his Ph.D. in Biochemistry from Peking University. He then completed his postdoctoral training in proteomics at University of Michigan – Ann Arbor, and pursued further training in mass spectrometry at Pacific Northwest National laboratory. Dr. Jintang He joined Genentech in 2014 and his research interests include developing novel mass spec technologies to quantify monoclonal antibodies and biomarkers, as well as to characterize in vivo biotransformations of biotherapeutics.

Appearances:



Festival of Biologics Day 3 @ 12:10

Targeted 2D-LC-MS/MS technology with enhanced sensitivity to assess KRAS G12C target engagement in core needle biopsies

·       Targeted 2D-LC-MS/MS enabled quantification of biotherapeutics and biomarkers down to pg/mL range without the need of custom antibody reagents

·       Hybrid immunoaffinity enrichment with targeted 2D-LC-MS/MS provides the most direct approach for understanding KRAS G12C target engagement

·       Understanding target engagement at the site of action in tumor tissues provides critical insights for drug development

last published: 27/Mar/24 15:25 GMT

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