Jenny Wei | Sr. Director, R&D Informatics and Technology
Kite Pharma
Jenny Wei is the Head of R&D Informatics and Technology at Kite Pharma. She has over 24 years of experience in biopharma industry building digital strategy, delivering AI/ML solutions & advanced analytics to accelerate small molecule, biologics, and cell therapy research & clinical Development, real-world evidence generation, process development, clinical manufacturing and supply chain. Trained as a biologist and a computer scientist, she holds a Master’s in Computer Science from Rutgers University and a Ph.D. in Pharmacology from University of Washington.
Appearances:
Festival of Biologics Day 1 @ 14:20
AI/ML Augmented CAR Discovery
CAR T Cell Therapy is a type of immunotherapy that holds the potential to cure cancer and autoimmune diseases. Since the first CAR-T cell product was approved by the FDA in 2017, five additional CAR-T cell products have reached the market, all of which target CD19 or BCMA. Conventional wet lab approaches to CAR discovery can be costly and time consuming. Our AI/ML Augmented CAR Discovery initiative is aimed at revolutionizing the process with 4 strategic pillars: High-throughput wet lab automation; Cloud based CAR engineering and screening data foundation; Optimized ML algorithms; High performance computing pipelines. At Festival of Biologics, we will present in silico CAR binder optimisation technologies, with a focus on binder-antigen complex structure prediction, stability and affinity assessment with NQ-FEP and CAR language model for CAR property predictions.
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