Agenda Day 2

BioData West: Day 2

Edward Glanville
08:45

Producers opening remarks

Sylvain Costes
08:50

NASA GeneLab Project: using multi-omics to understand how space impacts life

  • Inferring knowledge from diverse datasets using new NASA tools 
  • GeneLab data: factors influencing life in the space shuttle and the ISS including radiation and microgravity and what this means for humans back on earth 
  • How to engage a larger community via higher order data and analysis working group
  • How to transfer the power of NASA based technologies into healthcare through collaborative efforts like NCI and NASA
Greg Corrado
09:00

Large Scale Deep Neural Networks to empower diagnostics and drug development: learnfrom the company at the bleeding edge of AI

  • Developing Google’s largest deep scale network – How do 16,000 computers studying 10 million images of cats help towards developing early diagnostics for disease? 
  • Understand the power of deep neural networks and develop new targets and implement powerful deep learning networks to empower drug discovery
  • Open source tensor flow platforms -taking your drug development full steam through the world’s most powerful open AI chip 
Amit Rastogi
09:40

Developing the Inova Precision Medicine Roadmap: Convergence of implementation science, precision medicine, and the learning healthcare system

  • What are the challenges faced when implementing a system wide precision medicine platform across a healthcare system ?
  • Developing a harmonized road map for the implementation of precision medicine- Real world case studies on implementation of precision medicine at Inova
  • What were the financial implications and how can the model benefit your precision medicine implementation strategy?   
  • Collaborations and partnerships with vendors to make the process work  How to make it a success story through developing early stage frameworks? 
10:00

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10:20

MORNING REFRESHMENTS

GENOMICS AND HEALTH

PRECISION MEDICINE

ARTIFICIAL INTELLIGENCE

GENOMICS & HEALTH
11:00

How do you use metadata to unlock the true potential of health data?

  • Taming the stream of bytes- why disseminating data is not enough- How tagging and curating maximizes the capability of your data
  • New directions in data curation- how new strategies have been developed out of ICPSR to allow for easy accessibility and retrieval of data
  • How metadata enhances discovery, use, and preservation- maintenance of data is key – do you do enough? 
PRECISION MEDICINE
11:00

Collaborations with Industry to accelerate rare disease discoveries in the fastest way possible

  • How to structure relationships to protect the interests of all parties when dealing with rare diseases
  • What are the required infrastructure to make partnerships work?
  • Understanding the importance of phenotyping, transparency, and patient engagement
ARTIFICIAL INTELLIGENCE
11:00

Brain Genomics and machine learning- How to get a deep dive into the world of brain genomics?

  • Review of the history and taxonomy of machine learning and artificial intelligence
  • Introducing deep learning- How is its power increasing and how will it will change the face of healthcare?
  • Concrete applications of AI to life sciences problems (calling SNP and indel variants in next-generation sequencing data & detection of diabetic retinopathy from fundus images of the eye)
GENOMICS & HEALTH
11:20

IT infrastructure to speed the delivery of Precision Medicine into the clinic

  • How to develop an efficient network architecture to empower research across your institution
  • New requirements for the big data era are chancing - how are you preparing 
  • Customized working environments:using multi scenario prioritization to put the dollars back into the researcher’s pocket and save computing power 
PRECISION MEDICINE
11:20

Biobanks - propelling precision medicine into the clinic in the fastest way possible

  • Hear how Kaiser Permanente has implemented precision medicine within its existing nationwide healthcare system 
  • How biobanks with research ready biospecimens and associated EMR data pave the way for the development of further physical tied to EMR databases
  • How digitalization of biobanks allows efficient access to specimens empowering researchers to get what they need in the fastest and efficient way possible
ARTIFICIAL INTELLIGENCE
11:20

Developing trials of the future

  • How wearables are changing patient centeredness and compliance for clinical trials
  • Digital Biomarkers and Digital Therapeutics: See how digitalization leads to better efficiency and insights 
  • Developing large wearables trials - the lessons learned from building arrhythmia data sets through wearables
GENOMICS & HEALTH
11:40

Developing an ecosystem in which EHR and genomic data can flow freely

  • Elements of MVP (Million Veterans Program): the direction for the future, and strategies to transform genomic efforts into the clinic
  • Building one of the world's largest medical databases by safely collecting blood samples and health information from one million Veteran volunteers
  • How to manipulate one of the largest genomic data sets in the world 
  • Future use of MVP data to enhance the health of veterans
PRECISION MEDICINE
11:40

Rare diseases and precision medicine

  • Accelerating development of novel therapeutics through the transition of genomic data into the AI based drug development 
  • Driving patient centricity through big data to drive cures to the patient in the fastest way possible 
  • Intercalating genomics and EHR records in an efficient and secure manner to drive forwards trail recruitment
ARTIFICIAL INTELLIGENCE
11:40

Computational Drug Discovery using Artificial Intelligence

  • Learn novel Deep Learning for design of new molecules
  • Benefits of AI for increasingly more accurate property predictions
  • Combining multi-modal data streams into predictive modeling workflow
  • ADME/Tox and off-target property optimization with AI methods 
GENOMICS & HEALTH
12:00

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PRECISION MEDICINE
12:00

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ARTIFICIAL INTELLIGENCE
12:00

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12:20

NETWORKING LUNCH

GENOMICS & HEALTH
13:40

"Quantum Technology and QuantumBio" – an analysis

  • Hear the background and history of quantum and how it relates to the future of medicine
  • Understand the potential and the benefits of quantum tech in healthcare? 
  • Who are the Discuss key research teams, vendors, technologies and the most forward-thinking research?
PRECISION MEDICINE
13:40

Scaling real world collective intelligence

  • Prediction: Gaining insights into new platforms to drive a new paradigm of AI
  • Precision: Develop a new understanding of the precision machine learning techniques that empower precision.
  • Prevention: Stabilizing patients before symptomatic onsets
ARTIFICIAL INTELLIGENCE
13:40

Developing translational medicine through the three main pillars: benchside, bedside and community

  • How to enable the transition of knowledge between the three pillars of translation
  • Utilizing digital technologies to empower collaboration to accelerate research 
  • Understanding the educational road map and processes across the translational field
GENOMICS & HEALTH
14:00

Scalable quantum simulation of molecular energies: Towards an exact (quantum) description of chemistry

  • Understanding the advantages of the discipline in the acceleration of research 
  • How molecular energy functions can be be defined by quantum computing faster than by classical models 
  • Understand the advantages of quantum for your drug development process and assess the impact on computing power 
PRECISION MEDICINE
14:00

The genetics of drug efficacy: opportunities and challenges

  • How efficacy has become the most common cause of attrition in late-phase drug development
  • Driving the application of efficacy pharmacogenetics into drug discovery and development across industry
  • Defining the value of routine, early and cumulative screening for genetic predictors of efficacy, as an integrated component of clinical trial analysis
ARTIFICIAL INTELLIGENCE
14:00

Tools to accelerate testing of new Parkinson's treatments by assisting in trial design and subject stratification

  • Identifying early clinical markers of rate of progression – how to benefit clinical care and testing of new therapies  
  • Characterizing subgroups based on clinical symptoms – how to allow trial sponsors to test new therapies 
  • Developing new avenues for investigations – how pathophysiology can be targeted in a more efficient way through AI 
GENOMICS & HEALTH
14:20

Understanding the power of Quantum Computing in Drug Discovery

  • Using Quantum computing to transform traditional R&D drug discovery processes, improve speed and productivity alongside significantly reducing costs and accelerating access to new therapies for patients
  • Unveiling a first-of-its-kind quantum-enabled molecular comparison application that could significantly improve advanced molecular design to speed up drug discovery for complex neurological conditions
  • Solving complex business problems millions of times faster than classical computing by leveraging the properties of quantum physics in computing
PRECISION MEDICINE
14:20

Intermountain Precision Genomics for Everyday Patients

  • Developing efficient and rapid diagnostic processes using WGS and gene panels
  • Comparing WGS and gene panels in areas such as cost vs time implications and he future of the technology
  • Navigating care pathways with the guidance of genomics data to provide economic value to institutions
ARTIFICIAL INTELLIGENCE
14:20

What would patients say if you asked them?

  • How patient experience is changing the way pharma thinks about drug development
  • What patients can share with pharma: now and in the future
  • What are the key lessons learnt from the frontline of patient engagement?
GENOMICS & HEALTH
14:40

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PRECISION MEDICINE
14:40

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ARTIFICIAL INTELLIGENCE
14:40

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15:00

AFTERNOON REFRESHMENTS

POST CONGRESS SHORT COURSES

PRECISION MEDICINE
15:40

PRECISION MEDICINE 101

  • An overview of the clinical applications of genomic medicine, skills to evaluate clinical validity and utility of new tests, and the associated ethical and social issues inherent to genomics
  • Conceptual and practical information about real-world applications of genomics
ARTIFICIAL INTELLIGENCE
15:40

ROUND TABLES

Round Table 1
Augmenting Human Intelligence through AI
Prasun Mishra, Founder and CEO Agility Pharmaceuticals, CEO, American Association for Precision Medicine  

Round Table 2
Tensor Flow - Developing a greater understanding of the chip and its possibilities

Round Table 3 
The Power of Epigenomics- From Age Prediction to Precision Medicine
Jeffrey Bhasin, Director of Informatics, Zymo

Round Table 4 
Bayes DB- Understanding systems for implementing AI for the layman
Vikash Mansinghka, Principal Investigator, MIT Probabilistic Computing Project, MIT
Veronica Weiner, CEO and Co-Founder, Resiliance Therapeutics, Director of Special Projects, MIT Probabilistic Computing Project

Round Table 5
Graph Databases - A short introduction

Round Table 6
Sequencing Populations- How to make it effective and fast

Round Table 7 
AI in Drug Discovery- Partnering with new AI and tech companies

Round Table 8
Policy and Governance- Update on current legal implications 

Round Table 9- 
Aging and Drug Development- How investment in aging is becoming an essential topic

Round Table 10- 
Policy and Governance

Round Table 11- 
Cancer Diagnostics- Liquid biopsies 

Round Table 12- 
Multimodel Integration- New AI methods
 
17:10

END OF BIODATA WEST 2018

last published: 11/Dec/17 21:15 GMT