Bacteria cultured in vitro are more susceptible to antibiotic effect than in patients. More representative platforms would decrease the number of “false positive” antibiotic candidates that carry significant costs until true efficacy is tested during clinical trials.
Bac3Gel is a revolutionizing substrate for bacteria culture, solving this problem by mimicking the physicochemical properties of human mucus, where bacterial infections thrive. Bac3Gel is able to model any type of mucus, in healthy or pathological states, with an antibiotic barrier effect similar to physiological effective doses. Allowing efficient screening at the in vitro stage of antibiotic development, cumulatively saving costs later on.