Gavilán Biodesign uses its proprietary computational chemistry approach to develop novel antineoplastic therapeutics that are resilient to the emergence of drug resistance. The ability of cancer to develop resistance to therapeutics is the number one contributing force to mortality. Gavilan is building on the success of the OSPREY software package developed in the Donald lab at Duke University, expanding it to not only predict but also design new molecules capable of overcoming drug resistance.
On the left, we can see our proprietary scaffold redesign and hopping technology SOCCER. SOCCER generates scaffold diversity while maintaining important interactions and avoiding clashes with the binding pocket or interface.