The Japan Agency for Medical Research and Development (AMED) was established on April 1, 2015 to engage in research and development in the field of medicine, establishing and maintaining an environment for this R&D, providing funding and managing R&D projects. AMED focuses on promoting integrated medical R&D from basic research to practical applications, to smoothly achieve application of outcomes, and to achieve comprehensive and effective establishment / maintenance of an environment for medical R&D. AMED implements these tasks based on the Healthcare Policy determined by the Cabinet and on the Plan for the Promotion of Medical R&D by the Headquarters chaired by the Prime Minister. AMED consolidates budgets for research expenses, which had previously been allocated from different sources -- the Ministry of Education, Culture, Sports, Science and Technology (MEXT), the Ministry of Health, Labour and Welfare (MHLW), and the Ministry of Economy, Trade and Industry (METI), resulting effective management of researches.