Dr Manish Sadarangani | Assistant Professor, Pediatric Infectious Diseases, University of British Columbia Director, Vaccine Evaluation Center
BC Children?s Hospital Research Institute

Dr Manish Sadarangani, Assistant Professor, Pediatric Infectious Diseases, University of British Columbia Director, Vaccine Evaluation Center, BC Children?s Hospital Research Institute

Dr Manish Sadarangani is Director of the Vaccine Evaluation Center at the BC Children’s Hospital Research Institute and an Assistant Professor in the Division of Infectious Diseases, UBC Department of Pediatrics. He completed his undergraduate medical training and pediatric residency in Cambridge, Oxford and London in the UK. He then completed his DPhil with the Oxford Vaccine Group in the UK, developing novel vaccine candidates for protection against capsular group B meningococcal disease, and completed a Fellowship in Pediatric Infectious Diseases in Vancouver in 2013 before returning to Oxford to work as a Pediatric Infectious Diseases physician. He is involved in pre-clinical vaccine development, multi-center clinical trials and infectious diseases epidemiology. Specific research interests include meningococcal disease and meningococcal vaccines, bacterial conjugate vaccines, meningitis and encephalitis, maternal immunization, the microbiota and antibiotic resistance and antimicrobial stewardship.

Appearances:



Agenda Day 1 @ 11:45

The Human Vaccine Project’s first clinical trial: Understanding the rules of lifelong immunological protection

  • The importance of looking at all aspects of immune response and integrating this data to get an accurate reflection of response to vaccination
  • What distinguishes the 30% of people who have a good response after a single dose of Hep B vaccine
  • Results from initial study assessing immune responses of 10 healthy adults (ages 40-80) to a licensed hepatitis B vaccine, expansion into larger numbers and demographics
  • Outlook for 2018 and beyond:  projects looking at HPV vaccination – challenges to overcome

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