Established in 2006, Vitro Software has concentrated on developing patient focused eHealth solutions. Vitro is being used in more than 80 client sites and is benefitting thousands of clinicians and patients across the globe. In 2014 Vitro developed a dedicated Cystic Fibrosis registry and clinical management system. In 2015 Vitro set up an international cleft pallet registry and clinical patient management system. This is being used to collect clinical data and help manage surgery for thousands of cleft pallet patients in the sixty countries that Operation Smile is active in. By winning the joint tender with OpenApp in 2016 to provide the initial ICT platform for the European Reference Networks, Vitro is committed to a significant investment in ERNs.