Innovations, technologies and methodologies in driving drug discovery developme across Asia
Dr. Swaine Chen | Senior Investigator NUS, Genome Insititute of Singapore
Swaine Chen received his Ph.D. in Developmental Biology and an M.D. from Stanford University in 2004. He became interested in applying computational tools to infectious diseases during his post-doc in the lab of Scott Hultgren, Ph.D. at Washington University. Since 2010, he has been a Senior Research Scientist at the Genome Institute of Singapore and an Assistant Professor at the National University of Singapore in the Department of Medicine, doing research on new computational methods for probing host-pathogen interactions. By focusing on evolutionary methods, the pathways most relevant for pathogen survival and thus most interesting from a therapeutic perspective may be identified. He has worked specifically on E. coli that cause urinary tract infections, but the computational methods are easily generalized to other infectious diseases.
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Appearances at this years' conference:
Conference Day 2: 21 March 2012
@ 16.20
Deduction of novel phenotypes and disease mechanisms in uropathogenic E.coli using comparative evolutionary analysis
Analysing a case study to making use of increased DNA sequence availability
Effective translation of sequence data in silico into new mechanistic insights in vivo using the FimH protein
Advantages of in silico evolutionary approaches for identification of in vivo phenotypes
› Dr. Swaine Chen, Senior Investigator, NUS, Genome Insititute of Singapore