Dr Thomas Ryll | Senior Director, Cell Culture Development
Biogen Idec

Dr Thomas Ryll, Senior Director, Cell Culture Development, Biogen Idec

Thomas completed his PhD in Biochemistry and Biotechnology in 1992 at the Technical University of Braunschweig, Germany. After a year PostDoc he joined Genentech in 1993. At Genentech he was involved in the development of the first generation of commercial antibody processes and other recombinant proteins including Fc-fusions, proteases, viral antigens and growth factors. In 2000 Thomas joined Abgenix as Senior Scientist and Associate Director, Cell Culture Development. His responsibilities included development of Abgenix’s proprietary expression system based on cell:cell fusion, development of efficient media and fed-batch process formats for antibody production, scale-up, CMC management and facility designs. In 2003 Thomas joined Tanox as Director and Senior Director of Process Development and member of the management team. Responsibilities included all activities from cell line generation, cell culture, purification and formulation development and analytical support. In 2006 Thomas joined Biogen Idec as Director and Senior Director of Bioprocess Development and is currently acting in this role. His responsibilities encompass all aspects of cell culture development including expression technology, cell line development, process development, scale-up, technology transfer and manufacturing support. His special interests include the alignment of biology and engineering aspects for development of efficient manufacturing processes.

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Appearances at this years' conference:

DAY 1 - Tuesday 28th February 2012


@ 09.40
Combining elements of process intensification, single use systems and advanced monitoring and control technology for the next generation cell culture processes

  • Can disposable bioreactors support intensified culture formats delivering high titers?
  • Exploring how the application of Raman Spectroscopy to culture monitoring and control can help improve process understanding and aid future developments
  • What will the next generation culture process likely look like?

  • › Dr Thomas Ryll, Senior Director, Cell Culture Development, Biogen Idec
@ 16.50
Panel discussion: evaluating the opportunities to develop cell culture bio-production

  • Given the need to produce biologics faster and cheaper, what strategies are the industry looking to in the future to achieve this?
  • Can understanding the benefits and limitations of different cell culture procedures aid in achieving the desired product in the shortest time with maximum yields?
  • Evaluating current technologies and methodologies which could deliver an optimized end-to-end production systems

  • › Dr Thomas Ryll, Senior Director, Cell Culture Development, Biogen Idec
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