Dr Hervé Broly | Vice President Biotech Process Sciences
Merck Serono

Dr Hervé Broly, Vice President Biotech Process Sciences, Merck Serono

Starting with an Engineering degree coupled with a doctorate in Physiology, Hervé Broly developed the manufacture of monoclonal antibodies for diagnostic reagent and therapeutical use at the Regional Blood Transfusion Center of Lille (France) from 1982 to 1991 and then at a subsidiary of Serono located in Bordeaux (France) from 1991 to 2003. From November 2003 to October 2006, Hervé Broly has been working as Program Director for the development of a recombinant protein for therapeutic use (atacicept) at Serono Corporate (Geneva, Switzerland) and then from November 2006 as Vice-President, Head of Biotech Process Sciences and Center of Expertise Biotech Bulk Manufacturing for Merck-Serono (Vevey, Switzerland). Current research focus relates to the improvement of the Merck Serono technology platform for the manufacture of McAbs and Fc-fusion recombinant proteins, to applying Quality by Design approach for the manufacture of bulk drug substance, and to the development of novel approaches for downstream processing.

Share this

Appearances at this years' conference:

DAY 1 - Tuesday 28th February 2012


@ 09.10
Applying QbD concept for the manufacture of biotech drug substance: is the design space dependent or independent of scale?

  • Merck Serono has developed the concept of Global Multi-step Design Space
  • The Design Space is almost developed on the basis of DoE experiments done at small-scale
  • Small-scale models were qualified by comparison with large-scale data obtained at central points
  • Are the limits of the Design Space still valid at manufacturing scale?

  • › Dr Hervé Broly, Vice President Biotech Process Sciences, Merck Serono
@ 16.50
Panel discussion: evaluating the opportunities to develop cell culture bio-production

  • Given the need to produce biologics faster and cheaper, what strategies are the industry looking to in the future to achieve this?
  • Can understanding the benefits and limitations of different cell culture procedures aid in achieving the desired product in the shortest time with maximum yields?
  • Evaluating current technologies and methodologies which could deliver an optimized end-to-end production systems

  • › Dr Hervé Broly, Vice President Biotech Process Sciences, Merck Serono
Sponsors
Gold & Lunch Sponsor
Irvine Scientific at Cell Culture World Congress 2012
Gold Sponsor
BD Biosciences at Cell Culture World Congress 2012
Gold Sponsor
Cevec Pharmaceuticals GmbH at Cell Culture World Congress 2012
Gold Sponsor
PAA Labs at Cell Culture World Congress 2012
Gold Sponsor
Catalent Pharma Solutions at Cell Culture World Congress 2012
Gold Sponsor
Merck KGaA at Cell Culture World Congress 2012
Gold Sponsor
Life Technologies at Cell Culture World Congress 2012
Drinks Reception Sponsor
Lonza at Cell Culture World Congress 2012
Associate Sponsor
Roche Diagnostics GmbH at Cell Culture World Congress 2012
Associate Sponsor
GE Healthcare at Cell Culture World Congress 2012
Associate Sponsor
Leica Microsystems at Cell Culture World Congress 2012
Associate Sponsor
Metabolon Inc at Cell Culture World Congress 2012
Associate Sponsor
Metanomics Health GmbH at Cell Culture World Congress 2012
Associate Sponsor
SAFC at Cell Culture World Congress 2012
Exhibitor
Bayer Technology Services GmbH at Cell Culture World Congress 2012
Exhibitor
VIVALIS SA at Cell Culture World Congress 2012
Exhibitor
Caridian BCT at Cell Culture World Congress 2012
Exhibitor
Wuhan Healthgen Biotechnology Co. Ltd at Cell Culture World Congress 2012
Exhibitor
Nova Biomedical at Cell Culture World Congress 2012
Literature Sponsor
SciLog Inc at Cell Culture World Congress 2012
Literature Sponsor
CerCell Aps at Cell Culture World Congress 2012