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 Dr Dai Hongyue,
Senior Scientific Director, Molecular Profiling Data Analysis, Molecular Profiling Research Informatics Merck Research Labs, United States Hongyue Dai currently holds the Senior Scientific Director position of Molecular Profiling Data Analysis In Molecular Profiling Research Informatics of Merck Research Labs. His responsibilities include managing the molecular profiling data analysis support to various therapeutic franchises within Merck for target identification, biomarker discovery, compound prioritization and translating biomarkers in clinical trials. His current research interest is to use molecular profiling to study cancer.
He joined Rosetta in January of 1998 as a senior data analyst. In the early days of Rosetta, he worked closely with the biologists and engineers to develop and improve the inkjet microarray platform. He identified numerous artifacts related to microarray and sample handling processes and worked with the technology team to minimize the systematic biases. He also co-developed the first microarray data error model to characterize the data uncertainty. His most recent publications are cancer research related, including a Nature and a NEJM publication on breast cancer prognosis, a follow up data analysis on Cancer Research about breast cancer patient stratification, and a PNAS publication about CML disease progression. He made significant contribution to the first FDA approved multi-gene test kit for breast cancer prognosis, the MammaPrint. He also collaborated with Celera to develop the 14-gene test kit for ER-positive breast cancer patients.
He was a Research Associate Professor of Physics Department at University of Utah before joining Rosetta. He earned his credit as a solid data analyst by convincingly proving to the high energy astrophysics world the existence of cosmic rays beyond the 3oK microwave cutoff energy, through the discovery and careful analysis of a single event (It was commonly accepted that the microwave background eliminates all those cosmic rays). His analysis results about the cosmic ray energy spectrum and composition were published in Physical Review Letters and were widely cited.
He received his BS from Peking University and PhD from Institute of High Energy Physics of Chinese Academy of Science.Appearing: Conference Day One: Wednesday, 17 March 2010 14.30 Molecular analysis of tumor and adjacent tissues to identify HCC targets Dr Dai Hongyue, Senior Scientific Director, Molecular Profiling Data Analysis, Molecular Profiling Research Informatics,
Merck Research Labs, United States |
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asia research institution poster presentation
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